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Berberine HCL
    • Main Bottle
    • Back of bottle
    • Suggested use
    • Supplement Facts
    • Product advantages
    • Product benefits
    • Supports healthy bloodsugar metabolism
    • Made with natural ingredients
    • Supports healthy weight management

Berberine HCL

Clinical Effects Berberine HCL is a powerful natural supporter of already healthy blood sugar levels, weight management, heart and liver health. Sourced from various plants including barberry, Berberine HCL has been used for centuries for a range of health promoting properties. This expert formulated supplement supports healthy blood sugar metabolism, promotes heart health, and much more.

Berberine HCL

"Clinical Effects Berberine HCL has revolutionized my metabolic health."

- Clinical Effects Customer

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"Clinical Effects Berberine HCL has revolutionized my metabolic health."

- Clinical Effects Customer


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  • 180-day money back guarantee

7 Powerful benefits

Here are 7 science-backed reasons to try us out today.

Blood sugar tester


Berberine HCL can help maintain already healthy blood sugar levels.



Supports healthy heart function and blood vessel health.



Supports weight management to maintain a healthy weight.



Helps maintain healthy cholesterol levels already in the normal range.



Supports a healthy inflammation response.

Heart pressure


Helps maintain already-healthy blood pressure.



Supports liver health and healthy liver function.

What's Inside Berberine

Berberine HCL (Berberis Aristata)

Bring Your Foundational Health Into Focus

  • Supports Heart Health
    Maintaining good cholesterol levels is important for heart health. Research has shown, Berberine HCL can help support healthy cholesterol levels.
  • Supports Healthy Blood Sugar Metabolism
    Berberine HCL helps maintain healthy blood sugar levels by helping carbohydrates breakdown slowly.
  • Assists in Weight Management
    Berberine (the compound) is known to bind to enzymes in the body to regulate how they work. This includes enzymes that play a role in regulating metabolism and the growth of fat cells.
  • Promotes Liver Health
    A build-up of fat in the liver in someone who drinks little or no alcohol can lead to NAFLD. Berberine HCL may help reduce this build-up leading to better liver health.
  • Cruelty-Free & Sustainable
    Feel good knowing that Clinical Effects products are never tested on animals and our manufacturing process is friendly to the environment.
  • Support healthy blood sugar metabolism
  • Promote heart health
  • Support healthy weight management
  • Help maintain already healthy cholesterol levels
  • Support a healthy inflammation response
  • Help maintain already healthy blood pressure
  • Promote liver health

Why Customers Love Clinical Effects Berberine HCL

  • "This helps me to boost my energy and also to get in the best mood possible"

    Abraham Hernandez

  • "It gives me energy and it helps support my blood sugar levels"

    Karissa Psathas

  • "I can say that my stress level has been lower and I have been sleeping better"

    Andreia Oliveira

More About The Product

  • Directions

    Take two (2) capsules of Berberine HCL daily, ideally 20-30 minutes prior to a meal with a glass of water, or as directed by your healthcare provider.

  • Shipping Info

    Do You Ship Worldwide?
    We currently only ship to the United States and Canada.

    When Can I Expect My Order?
    Once you place your order, the warehouse ships it within 48 hours. You should receive it within 3 - 5 days post shipping.

    Will I Have To Pay Taxes And Duties?
    This depends on the state you reside in. In most cases your order covers all costs.

    I’m Having Problems Tracking My Order.
    Please look for an email with a tracking link from USPS. In case you cannot find it, please get in touch with us and we'll help you out.

    What Is Your Return Policy?
    We offer a 180-day money-back guarantee with all of our orders. Request a return within 180 days if you are not satisfied.

    How Long Do Refunds Take To Process?
    As soon as we receive your return, the refund will be processed. Zero delays (unless it's a weekend)

    What Should I Do If I Received The Wrong Order?
    Please get in touch with our customer service team and they will ship the correct product at no cost to you.

More questions? Find answers on our FAQs page.

Reviews / Q&A

Product reviews are provided for informational purposes only and reflect solely the views and not those of Clinical Effects. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

      • Bib
        Checkmark icon

        Verified Purchase

        I’ve only been taking Berberine HCL for a little over a week, but my blood sugar levels have already begun to drop!

        Submitted on

      • Roxi
        Checkmark icon

        Verified Purchase

        I am 2 weeks into taking this supplement. I am anticipating good things ahead. So far I have noticed that my mood and mental alertness are clearer. I will know more at my next blood work up. Making changes to lower A1C, blood sugar, organ health etc. And weight loss. Wish me well.

        Submitted on

      • glenA
        Checkmark icon

        Verified Purchase

        great price

        Submitted on

      • Sam M.
        Checkmark icon
        Sam M.

        Verified Purchase

        I have looked for a Berberine supplement and I purchased Clinical Effects as soon as I saw them offering it.

        Submitted on

      • What Is Berberine HCL?
        Berberine HCL is a naturally derived compound found in numerous plants including European barberry and others. It has been utilized as a natural supporter of healthy blood sugar metabolism for centuries in both Chinese and Ayurvedic medicine. Research more recently has backed the health supporting properties of this powerful supplement which include heart and liver health support, weight management support and more.
      • How Do I Use Berberine HCL?
        Take two (2) capsules of Berberine HCL daily, ideally 20-30 minutes prior to a meal with a glass of water, or as directed by your healthcare provider.
      • How Quickly Will I See Results?
        Everyone responds to Berberine HCL in a different way. Some people may see an improvement within weeks and others may take months. Still others may have less of an effect. Rather than providing any particular results, Berberine HCL from Clinical Effects is intended to provide you with a natural, safe, and consistent source of this health promoting compound.
      • What Makes Berberine HCL So Useful?
        Berberine HCL from Clinical Effects offers an expert-formulated source of one of nature’s best blood sugar metabolism supporting compounds. Getting Berberine HCL in your regular diet would be extremely difficult without a supplement. This convenient daily supplement provides you with more concentrated levels of Berberine HCL than food sources.
      • Is This Safe To take Daily?
        Yes! All Clinical Effects products including Berberine HCL are expert-formulated, produced from high quality ingredients and lab tested.
      • Can Berberine HCL Reverse Health Problems?
        Berberine HCL is not intended to treat, diagnose, cure or prevent any illnesses. If you have any illnesses be sure to consult with your medical provider prior to taking Berberine HCL or any health supplement.
      • Is There A Guarantee?
        Yes! All Clinical Effects products are backed by an iron-clad 180-day money back guarantee. If you are not satisfied for any reason at all during this time period, request a no questions asked return.

Clean, Safe Ingredients

We're committed to developing products that are free from harmful ingredients.


Paraben Free


Sulfates Free


Cruelty Free


Plant Based




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